Physician Assistant vs Registered Nurse: pay, outlook, education and work, side by side.
Every row comes from one named source and says which career leads on that one dimension. There is no overall score.
Physician Assistant vs Registered Nurse: BLS classifies them as different occupations (SOC 29-1071 and 29-1141). The national median annual wage is $135,880 for physician assistants and $97,550 for registered nurses (BLS, May 2025). BLS projects national employment to change +21.1% for physician assistants and +5.6% for registered nurses from 2025 to 2035. Typical entry-level education: Master's degree vs Bachelor's degree. Which fits better depends on what you value; the table shows who leads on each dimension, with no overall winner.
Side by side
Data Differences smaller than a stated threshold read “About the same” (pay 5%, growth 2 points, openings 10%, one education level, ORS 10 points, O*NET 0.2).
Pick what matters to you; the matching rows are highlighted. Nothing is combined into a score.
| Dimension · source | Physician AssistantSOC 29-1071 | Registered NurseSOC 29-1141 | Leads on this dimension |
|---|---|---|---|
| Median annual wageBLS OEWS, May 2025 (national) | $135,880 | $97,550 | Physician Assistant |
| EmploymentBLS OEWS, May 2025 | 162,150 | 3,379,720 | Not ranked |
| Projected employment change, 2025–35BLS Employment Projections (national) | +21.1% | +5.6% | Physician Assistant |
| Projected numeric change in jobs, 2025–35BLS Employment Projections (national) · A count, not a rate: it scales with the size of the occupation. | +35,700 jobs | +194,700 jobs | Not ranked |
| Projected openings (annual average)BLS Employment Projections, 2025–35 | 11,500 a year | 180,800 a year | Registered Nurse |
| Typical entry-level educationBLS Employment Projections · typical, not a legal requirement | Master's degree | Bachelor's degree | Registered Nurse |
| Typical work experience in a related occupationBLS Employment Projections | None | None | About the same |
| Typical on-the-job trainingBLS Employment Projections | None | None | Not ranked |
| Telework available (share of workers)2025 preliminary BLS ORS | less than 5% | 1.1% | About the same |
| Pressure level (O*NET, 1–5; lower = less)O*NET® 31.0 work context | 4.09 | 3.97 | About the same |
| Social-contact level (O*NET, 1–5)O*NET® 31.0 work context · not ranked: neither direction is better | 4.70 | 4.67 | Not ranked |
| Freedom to make decisions (O*NET, 1–5)O*NET® 31.0 work context | 4.73 | 4.10 | Physician Assistant |
| Work styles O*NET rates most importantO*NET® 31.0 work styles (occupation ratings, not a personality test) | Attention to Detail, Dependability, Integrity | Attention to Detail, Dependability, Cooperation | Not ranked |
Choose based on what matters to you
Data Each line restates a measured difference from the table; nothing here predicts how you will feel about a job.
- higher median pay matters most ($135,880 vs $97,550)
- faster projected national growth matters (+21.1% vs +5.6%)
- more decision-making freedom matters (4.73 vs 4.10)
- a shorter typical education path matters (Bachelor's degree vs Master's degree)
Which skills each one leans on
Data O*NET 31.0 skill ratings: level (0–7) and importance.
Skill-profile match: 83% (similarity of the two O*NET skill profiles, importance × level; 100% = identical).
- Operations Analysis (+1.0 on O*NET's 0–7 skill-level scale)
- Science (+1.0 on O*NET's 0–7 skill-level scale)
- Systems Evaluation (+0.8 on O*NET's 0–7 skill-level scale)
- Time Management (+0.6 on O*NET's 0–7 skill-level scale)
- Operation and Control (+2.1 on O*NET's 0–7 skill-level scale)
- Equipment Selection (+0.9 on O*NET's 0–7 skill-level scale)
- Operations Monitoring (+0.9 on O*NET's 0–7 skill-level scale)
- Quality Control Analysis (+0.8 on O*NET's 0–7 skill-level scale)
What each career involves
Data Core tasks from O*NET 31.0.
Physician Assistant
- Make tentative diagnoses and decisions about management and treatment of patients.
- Interpret diagnostic test results for deviations from normal.
- Prescribe therapy or medication with physician approval.
- Obtain, compile, and record patient medical data, including health history, progress notes, and results of physical examination.
Registered Nurse
- Record patients' medical information and vital signs.
- Administer medications to patients and monitor patients for reactions or side effects.
- Maintain accurate, detailed reports and records.
- Monitor, record, and report symptoms or changes in patients' conditions.
Largest employing industries
Data Share of all jobs in each occupation, BLS Employment Matrix 2025.
Physician Assistant
- Ambulatory healthcare services (64.1% of all jobs in this occupation)
- Hospitals; state, local, and private (25.9% of all jobs in this occupation)
- Government, excluding state and local education and hospitals (3.0% of all jobs in this occupation)
Registered Nurse
- Hospitals; state, local, and private (59.1% of all jobs in this occupation)
- Ambulatory healthcare services (18.9% of all jobs in this occupation)
- Nursing and residential care facilities (5.8% of all jobs in this occupation)
Moving between these careers
Data The comparison shows which; the career-change guides show how.
- Physician Assistant → Registered Nurse: skills to build: Operation and Control, Equipment Selection, Operations Monitoring. Careers after Physician Assistant
- Registered Nurse → Physician Assistant: skills to build: Operations Analysis, Science, Systems Evaluation. Careers after Registered Nurse
Go deeper
Physician Assistant career hub · Physician Assistant salary · Physician Assistant how to become · Physician Assistant career change · Registered Nurse career hub · Registered Nurse salary · Registered Nurse how to become · Registered Nurse career change
Common questions
Which pays more, Physician Assistant or Registered Nurse?
Which is growing faster?
Which is better?
How this page is built
BLS classifies them as different occupations (SOC 29-1071 and 29-1141). Pay: BLS OEWS May 2025 national median for each occupation's SOC code. Outlook: BLS Employment Projections 2025–35 (growth, numeric change and annual openings are separate metrics). Requirements rows: 2025 preliminary BLS Occupational Requirements Survey, shown only when both roles have detailed-occupation estimates. Work environment: O*NET 31.0 work context. This page includes information from the O*NET® 31.0 Database by the U.S. Department of Labor, Employment and Training Administration (USDOL/ETA). Used under the CC BY 4.0 license. O*NET® is a trademark of USDOL/ETA. TryHired has modified all or some of this information. USDOL/ETA has not approved, endorsed, or tested these modifications. Searches this page answers include “physician assistant vs rn”, “physician assistant vs registered nurse”, “registered nurse vs physician assistant” (Ahrefs, U.S.).
- Any one employer's pay, schedule or culture.
- Job security, ease of hiring or work-life balance: these are not measured here.
- Which career you will prefer: the rows describe the occupations, not you.
- U.S. Bureau of Labor Statistics, Occupational Employment and Wage Statistics, May 2025 estimates (public domain).
- U.S. Bureau of Labor Statistics, Employment Projections program, 2025–35 national projections (growth, openings, typical entry-level education and experience).
- O*NET 31.0 Database, U.S. Department of Labor, Employment and Training Administration (USDOL/ETA), used under the CC BY 4.0 license. TryHired selected, ranked and combined the data; O*NET is not responsible for these pages.
- U.S. Bureau of Labor Statistics, Occupational Requirements Survey, 2025 estimates (preliminary: two of the third wave's samples, collected August 2023 to July 2025; released January 16, 2026), public domain.
- U.S. Bureau of Labor Statistics, Employment Projections program, 2025–35 National Employment Matrix (all jobs, including self-employed).