Registered Nurse salary in St. Louis, MO: $83,180 median.
BLS reports occupational wages for the St. Louis, MO-IL metropolitan statistical area (CBSA 41180), which includes St. Louis and surrounding communities. Figures describe that whole area, not St. Louis city limits. It spans Missouri and Illinois.
Registered Nurses in the St. Louis, MO-IL metropolitan area earned a median annual wage of $83,180 in May 2025, according to BLS (OEWS, SOC 29-1141); the OEWS mean annual wage was $88,310. That median is 15% below the U.S. median of $97,550. BLS estimates about 35,200 people work in this occupation across the metro.
Data Among the 368 metro areas whose estimate for this occupation meets TryHired's reliability rule, this metro ranks 208 by median wage.
Data Separately, BEA puts 2024 price levels across the St. Louis, MO-IL metropolitan area at 95.1 (U.S. = 100): prices for the average consumer are about 5% below the national level. That is context, not an adjusted salary.
What area these numbers cover
Data The BLS geography behind every figure on this page.
- Search label
- St. Louis, MO
- BLS source geography
- St. Louis, MO-IL
- Geography type
- Metropolitan Statistical Area
- CBSA code
- 41180
- States
- Missouri, Illinois
- Delineation
- OMB Bulletin 23-01, as used by BLS OEWS May 2025
Local, state and national pay
Data Same occupation (SOC 29-1141), same BLS release (May 2025). This metro spans more than one state; each state is shown.
| Geography | Median annual wage | Mean annual wage | Employment |
|---|---|---|---|
| St. Louis, MO-IL (metro, CBSA 41180) | $83,180 | $88,310 | 35,200 |
| Missouri (state) | $81,780 | $85,900 | 76,310 |
| Illinois (state) | $95,990 | $94,360 | 138,910 |
| United States | $97,550 | $101,420 | 3,379,720 |
Registered Nurse salary in Missouri · Registered Nurse salary in Illinois · National Registered Nurse salary · Careers in St. Louis, MO.
Data Nationally, BLS projects employment in this occupation to change +5.6% from 2025 to 2035. BLS does not publish metro projections in this dataset, so that is national context, not a local forecast.
Reliable metro medians in Missouri
Data Metro areas that include part of this state and pass the reliability rule.
Reliable metro medians in Illinois
Data Metro areas that include part of this state and pass the reliability rule.
Use the local number
Advice Uses only what you type. A local, sourced median is easier to agree to than a national one.
How this page is built
BLS OEWS May 2025 estimates for the St. Louis, MO-IL metropolitan statistical area (CBSA 41180) and SOC 29-1141 (Registered Nurses). St. Louis, MO is the search label for that area; BLS does not publish city-limit wages. Employment is the number of people working in the occupation (excluding the self-employed), not job openings. Ranks use only metro estimates that pass the reliability rule (500+ jobs, employment PRSE ≤ 20%, mean-wage PRSE ≤ 10%, non-degenerate distribution); suppressed values are never imputed. Searches this page answers include “rn salary in st. louis”, “rn salary in st louis mo”, “icu nurse salary st louis” (Ahrefs, U.S.).
- Cost of living: wages are not adjusted for local prices.
- Pay at a specific employer, in one city's limits, or for self-employed workers.
- Local outlook: BLS projections here are national.
- U.S. Bureau of Labor Statistics, Occupational Employment and Wage Statistics, May 2025 metropolitan-area estimates (2018 SOC; metropolitan statistical areas per OMB Bulletin 23-01), public domain.
- U.S. Bureau of Labor Statistics, Occupational Employment and Wage Statistics, May 2025 estimates (public domain).
- U.S. Bureau of Labor Statistics, Employment Projections program, national occupational projections 2025–35 (no metro projections are published in this dataset).
- U.S. Bureau of Economic Analysis, Regional Price Parities, 2024 (released February 19, 2026).
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