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Salary · Registered Nurse · South Carolina

Registered Nurse salary in South Carolina: $82,360 median.

How pay for registered nurses in South Carolina compares with the national figure and other states, and where in the state it is highest.

Updated Oct 24, 2026 · Data: BLS OEWS May 2025
Annual wage range · South Carolina · BLS May 2025
$82,360median in South Carolina

Quick answer

Registered Nurses in South Carolina earned a median of $82,360 a year in May 2025 (BLS), 16% below the national median of $97,550. South Carolina ranked 39 of 51 for this occupation's median pay, with about 49,750 people employed.

South Carolina median
$82,360
$39.60/hr
U.S. median
$97,550
-16% in South Carolina
Rank among states
39 of 51
by median pay
Employed
49,750
location quotient 0.99
Metro areas

Where in South Carolina it pays most

Data Metropolitan areas in the state with at least 30 people employed in the occupation.

  1. Charleston-North Charleston, SC$92,800
  2. Charlotte-Concord-Gastonia, NC-SC$90,620
  3. Augusta-Richmond County, GA-SC$87,760
  4. Sumter, SC$86,260
  5. Spartanburg, SC$82,360
  6. Columbia, SC$81,920
  7. Greenville-Anderson-Greer, SC$81,400
  8. Hilton Head Island-Bluffton-Port Royal, SC$81,400
Nearby in the ranking

States with similar pay

Data Ranked by state median, BLS May 2025.

  1. Oklahoma$82,920
  2. Ohio$82,510
  3. South Carolina$82,360
  4. Missouri$81,780
  5. Tennessee$81,500

See all states on the national Registered Nurse salary page.

Keep exploring

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Method

How this page is built

BLS OEWS state and metropolitan-area estimates for May 2025, for the occupation shown. Ranks compare state medians only.

What this page can't tell you
  • Cost of living, which changes what a salary is worth.
  • Pay at a specific employer or for self-employed workers.
Sources
  1. U.S. Bureau of Labor Statistics, Occupational Employment and Wage Statistics, May 2025 estimates (public domain).